Would you trust taking this car on a high mileage drive?

I have a 2005 ford f150. 4 wheel drive 5.4 v8. It has 260,000 miles. So far I’ve put a rebuilt engine in (20,000 ago) changed the oil, tires, alignment, tie rod, alternator, coolant flush, driveshaft/u-joint, a coil pack, previous owner did trans fluid. The truck is running absolutely fine and I have been treating it like new since I got it. Me and a few friends are taking it approx 250 miles (there and back) on Friday. I just hope it makes it because we will be out of state and kind of in the middle of nowhere. 260,000 is a lot of miles. I feel like it would make it there and back but what do you guys think?

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